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The Changing Physics of Cybersecurity and Drug Development with OpenAI President Greg Brockman

No Priors · 2026-10-15

Speaker 1 | 00:00 - 00:19
To ensure AGI benefits all of humanity, we think that humans should be firmly in the driver’s seat, should have control over the future, and this technology should amplify human agency. When I look at the world we’re going to be in, where software in some ways is becoming like the barrier to entry, it’s becoming so cheap. You don’t just want software. Right? You want software that is reliable, that is secure, that you can believe in.

Speaker 1 | 00:19 - 00:32
And so cyber spend, security spend should actually vastly outstrip software spend. I think that people have n…

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Swyx (@swyx)

  • ok i really need the prompt(s) for this video because this is near-kurzgesagt level clarity of explanation (not yet illustration) [66 ❤️]
  • i’ve been waiting to launch this show for almost a year! thanks to the Testers and to @NehallAgrawal @KaylinWardley for helping me put this together!

some behind the scenes from the shoot of our latest show!! [46 ❤️ 4 🔄]

  • @affaan @absurdistphil @aiDotEngineer full talk written up: [4 ❤️]

Boris Cherny (@bcherny)

  • Don’t sleep on Claude Slides. This is how I make slide decks now – no more googling “iphone frame svg” like the old days

Try it: [3025 ❤️ 100 🔄]

  • I could not imagine being productive without Claude Code Review. It runs on all of my PRs, and catches almost every bug before it goes it. This is a piece of the secret sauce that lets the team and I move so quickly while raising the quality bar [3399 ❤️ 105 🔄]

Thibault Sottiaux (@thsottiaux)

  • Also we just added slides support yesterday, try it out. Currently available in Pro, Business and Enterprise while we learn from your feedback. [556 ❤️ 12 🔄]
  • What is ChatGPT Space, that is the question. Endearingly awkward at times because it’s the actual team working on it. What would you like to see next? [1744 ❤️ 73 🔄]
  • And update your app to enjoy this gem [687 ❤️ 10 🔄]

Peter Yang (@petergyang)

  • Docs -> slides -> video -> rap battle as the ultimate form of communication.

Should I make another one like this? Not about the feud don’t worry :) [23 ❤️ 1 🔄]

  • @bot @spacexai If you enjoyed this, sign up for free to my newsletter to get my best AI and product guides.

Join 110,000+ subscribers here: [5 ❤️]

  • @bot @bot please monitor all replies to this thread and send me the best ones in a list in 24 hours [15 ❤️]

Amanda Askell (@AmandaAskell)

  • the rocket car is cool and i want one [971 ❤️ 25 🔄]

Amjad Masad (@amasad)

  • Your data belongs to you! We’ll deploy Replit to your cloud and data never leaves home.

Designed for high stakes environments like governments, finance, and healthcare. [144 ❤️ 11 🔄]

  • Frontier Slides, super fast ;) [103 ❤️ 6 🔄]
  • Fascinating to see Mathematicians go through all the stages of grief — Denial, Anger, Bargaining, Depression, and Acceptance — in such a compressed window of time.

We’re at the tail end of depression and entering acceptance. [651 ❤️ 40 🔄]

Guillermo Rauch (@rauchg)

  • ⣴⣿⣿⣿⣿⣿⣿⣿⣿⣿⣦
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    ⠻⣿⣿⣿⣿⣿⣿⣿⣿⣿⠟ [99 ❤️ 4 🔄]
  • Rebuilt the Roadster demo in a playable, highly accurate simulation that retains a lot of the IRL details: [602 ❤️ 22 🔄]
  • TypeScript is the new TypeScript 😂
    When 𝚜𝚌𝚛𝚒𝚙𝚝𝚌-compiled, outperforms tsgo by 2-4x [341 ❤️ 10 🔄]

Aaron Levie (@levie)

  • It’s incredible to have reached a threshold where it’s practical that AI will be better at training models than humans are so quickly. One day recursive self improvement feels far off, and the next we already have signs of what it will look like.

Model capability finally exceeding most human engineers, advancements in the harness and infra for long running agents, a growing array of data, and the ability to parallelize the agents to work on vastly more tasks and tests and approaches than any person could have before, creates an incredible flywheel.

This flywheel will almost certainly accelerate model progress far faster than we’ve seen before - or at a minimum enable pushing up the ceiling of the frontier at an insane rate. If you aren’t pricing in what RSI will lead to, that’s probably a mistake. [125 ❤️ 12 🔄]

Ryo Lu (@ryolu_)

  • [1 ❤️]
  • feelings

light piercing through the blinds
birdsongs by the window
coffee grounds, blooming

slow walk in the cypress forest
long breath, cold air
fuzzy raindrops tap on the skin
catching the waves
endless ocean, salt on the lips

train window, mountains sliding by
holding hands, running
through the yellow light
cold bath after a hot day
making you laugh like a kid again

eyes closed
listening to our favorite songs
cuddles and kisses
your breath slow on my neck
hearing my heart break

day by day, letting time pass
midnight to sunrise
life is beautiful, the way it is [102 ❤️ 1 🔄]

Garry Tan (@garrytan)

  • Want to try GBrain but don’t know how? is the best easiest hosted way to get going [130 ❤️ 7 🔄]
  • Starting a new project today, and my absolute favorite thing is @capydotai with @AsideAI means my agents can both code the first version and help me get all the DevOps set up in one fell swoop [187 ❤️ 6 🔄]

Matt Turck (@mattturck)

  • When an AI startup gets a compute allocation [81 ❤️ 6 🔄]

Zara Zhang (@zarazhangrui)

  • DM me if you’d like to learn how to make something like this! [6 ❤️]

Nikunj Kothari (@nikunj)

  • Shoot your shot, you never know how the universe collaborates in your favor..

I wrote this 7 months ago as my “prediction”, met ~50 odd startups in the space, and finally found the one that we get the privilege to lead the Series A for.

Perfect way to end the week 🙏 [91 ❤️]

  • founders trying to evade my “how do you actually calculate this revenue” question.. [89 ❤️ 2 🔄]

Dan Shipper (@danshipper)

  • generation is now cheap and high quality

the big capabilities bump we need is now editing and oversight [86 ❤️]

  • at show and tell today @leeknowlton demoing how he turned my Codex piece into a visual novel: [32 ❤️ 3 🔄]

Aditya Agarwal (@adityaag)

  • Spots to RSVP [2 ❤️]
  • Very excited to welcome a dear friend to @spc next week.

@sriramk is joining us for a fireside chat and Q&A.

He helped build Azure, scaled Meta’s mobile ads, and led a16z’s international expansion.

Then he went to the White House and helped write the U.S. AI Action Plan. [120 ❤️ 5 🔄]

Sam Altman (@sama)

  • The back of the Navier-Stokes milestone shirt is the last line of the chain-of-thought from the solution: [9023 ❤️ 410 🔄]
  • Wow the new roadster looks quite amazing, good job @elonmusk [55749 ❤️ 1581 🔄]
  • Very happy to see this from Nick! [2920 ❤️ 115 🔄]

Claude (@claudeai)

  • What are you making with Claude this weekend? [514 ❤️ 5 🔄]
  • Haiku 5.5 wrote twenty haiku, then drew every frame in JavaScript. [644 ❤️ 10 🔄]
  • A cardiology fellow built a 3D tool to help trainees learn to read coronary angiograms. [1506 ❤️ 67 🔄]

由 Follow Builders 自动生成 · 2026-10-17